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JOURNAL ARTICLE
RESEARCH SUPPORT, NON-U.S. GOV'T
Activating or Inhibiting Nrf2?
Trends in Pharmacological Sciences 2017 November
Activating nuclear factor erythroid 2 (NF-E2)-related factor (Nrf2) is a widely recognized strategy for combating oxidative-stress-induced diseases. However, Nrf2 activation does not always bring advantageous effects. Therefore, before performing Nrf2-targeted therapy, we must pinpoint whether Nrf2 should be activated or inhibited.
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