Incidental neuronal intermediate filament inclusion pathology: unexpected biopsy findings in a 37-year old woman with epilepsy.

We present unexpected neuropathological findings in a 37 year old woman who underwent surgery for removal of an epidermoid cyst. A first brain MRI at the age of 27 years (due to hyperprolactinemia) showed a cystic lesion in the right prepontine region involving the cisterna ambiens with supratentorial extension. The lesion remained stable until she was 32 year, when it increased in size causing partial compression of the parahippocampal gyrus, midbrain peduncle and lateral pons (Fig. 1). One year later, the patient started to present weekly seizures in form of partial focal complex seizures. At that point, she had neither cognitive decline nor behavioral alterations and she was independent for all daily activities. No family history of neurological or psychiatric disorders was known. She worked as a Catalan language teacher and no language problems were detected. This article is protected by copyright. All rights reserved.