Mean Platelet Volume and Platelet Count are Elevated in Patients with Subacute Thyroiditis.

BACKGROUND: Platelet parameters have been studied in many diseases. This study explored the changes of mean platelet volume (MPV) and platelet count (PLT) in subacute thyroiditis (SAT).

METHODS: We retrospectively studied 44 patients with SAT and 45 healthy individuals. Diagnosis was confirmed by pathologic examination of surgical specimens.

RESULTS: There were no significant differences in age and gender between the SAT group and the control group. We compared the above indexes between the two groups. WBC and PLT were significantly higher and MPV was obviously lower in the SAT group. PLT had high sensitivity for diagnosis of SAT.

CONCLUSIONS: PLT was elevated and MPV was decreased in SAT patients. A negative correlation between PLT and MPV was found.