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Promising effects of nanomedicine in cancer drug delivery.
Journal of Drug Targeting 2018 April
Successful ushering of nanomedicine has shown immense potential in advancing cancer treatment regimens. The unique characteristics of nanoparticles such as their optimal size, shape, efficient surface to volume ratio, surfaces that can be optimally tailored make them very attractive delivery candidates for highly hydrophobic chemotherapeutic agents. Moreover, their inherent capacity to encapsulate these drugs and enhance their solubility profiles offers them unique advantages over conventional treatments. Surface modification with targeting ligands, increased intracellular uptake and prolonged circulation profiles in vivo establish their overall superiority over other treatment regimens. This article attempts to highlight some of these salient features of nanoparticles as drug delivery agents, which makes them more attractive in terms of providing promising opportunities in targeted drug delivery.
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