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Journal Article
Research Support, N.I.H., Intramural
Patchy Parasitized Skin Governs Leishmania donovani Transmission to Sand Flies.
Trends in Parasitology 2017 October
Doehl et al. have combined empirical data with computer simulation to demonstrate that RAG-2 mice intravenously infected with Leishmania donovani form heterogeneous skin parasite patches that govern infectiousness to sand flies. This model provides a much-needed tool to explore the relevance of asymptomatic and symptomatic visceral leishmaniasis patients as infection reservoirs.
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