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Changes in Perioperative Systolic Blood Pressure in Percutaneous Renal Mass Cryoablation.

OBJECTIVES: To analyze changes in systolic blood pressure (SBP) in the perioperative period of percutaneous renal mass cryoablation and risk factors.

METHODS: This retrospective study included 54 patients who underwent percutaneous renal cryoablation. SBP before ablation (pre-Tx), during ablation (intra-Tx), immediately after ablation (post-Tx), and before discharge (discharge) were measured using a BP cuff. The highest SBP during cryoablation was regarded as SBP at intra-Tx. Antihypertensive agents were administrated when SBP was 160 mmHg or greater during cryoablation. Relationship between SBP at pre-Tx, pain degree, tumor size, cryoprobe number, or endophytic extension of the radiographic ice-ball, and SBP elevation or administration of antihypertensive agents was investigated.

RESULTS: Mean SBP elevation from pre-Tx to intra-Tx was 22.9 ± 18.0 mmHg (range -6-78 mmHg). SBP of intra-Tx was significantly higher than that of the other periods (p < .001), while SBP of post-Tx or discharge was similar with that of pre-Tx (p > .05). Tumor size (r = .324; p = .016), cryoprobe number (r = .300; p = .027), and endophytic extension (r = .348; p = .009) were correlated with SBP elevation, while SBP at pre-Tx or pain degree were not (p > .05). Antihypertensive agents were administrated for 24 patients (44.4%). In multivariate analysis, SBP at pre-Tx and endophytic ablation was associated with administration of antihypertensive agents during cryoablation (p < .05).

CONCLUSIONS: SBP elevation may occur during percutaneous renal mass cryoablation, but be improved before discharge. Endophytic extension of the radiographic ice-ball may be associated with significant BP elevation during ablation.

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