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Hepatotoxicity after high-dose intravenous methylprednisolone in multiple sclerosis patients.
Clinical Case Reports 2017 August
Hepatotoxicity is a rare adverse event of methylprednisolone that should be considered in clinical practice. In patients at risk, we propose liver function surveillance, by measuring hepatic enzymes concentration 15-30 days after methylprednisolone administration. Additionally, we propose ACTH, dexamethasone, or plasma exchange as alternate treatment options for these patients.
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