Comparison of efficiency of ethylenediaminetetraacetic acid, citric acid, and etidronate in the removal of calcium hydroxide intracanal medicament using scanning electron microscopic analysis: An in-vitro study.

CONTEXT: Being integral to root canal therapy, obturation can be performed adequately only after the removal of intracanal medicament. One technique involves the use of chelating agents such as ethylenediaminetetraacetic acid (EDTA) and citric acid. Etidronic acid, a relatively new chelator, has smear layer removal ability and lesser dentinal erosion. It is untested in calcium hydroxide (Ca[OH]2) medicament removal.

AIM: The aim of this study was to compare the efficiency of irrigation protocols (EDTA, citric acid, and etidronate) in Ca(OH)2 removal.

MATERIALS AND METHODS: Forty-five single-rooted mandibular premolars were decoronated, instrumented, and filled with Ca(OH)2. After 7 days incubation, Ca(OH)2 was removed by three irrigation protocols (Group-I: 17% EDTA; Group-II: 10% citric acid; and Group-III: 18% etidronate). Roots were split and analyzed (scanning electron microscope, ×1500). Chelator solution pH was tested. Data were analyzed by Kruskal-Wallis ANOVA and Mann-Whitney U-test.

RESULTS: Group-III (coronal-third) and Groups-I and II (middle-third) had highest cleanliness scores; Groups-II and III (apical-third) had lowest scores. Comparing the thirds, all groups showed difference in scores. pH of Groups-I, II, and III were 6.8, 1.4, and 0.3, respectively.

CONCLUSION: The solution pH of citric acid and etidronate impacts their Ca(OH)2 removal efficiency in different ways: the highly alkaline pH of Ca(OH)2 increases citric acid pH toward neutrality, where it becomes an inefficient chelator; on the contrary, high acidity of etidronate compensates for its weaker chelation. Etidronate may not require 5 min duration for Ca(OH)2 removal due to the likelihood of dentinal erosion.