We have located links that may give you full text access.
Biochemical and Histopathological Evidence on Beneficial Effects of Standardized Extract from Tragopogon graminifolius as a Dietary Supplement in Fatty Liver: Role of Oxidative Stress.
Journal of Dietary Supplements 2018 March 5
Nonalcoholic fatty liver disease (FLD) is a worldwide common liver disorder. Tragopogon graminifolius is used as a dietary supplement for liver disorders. This study aimed to assess the beneficial effects of a standardized preparation from T. graminifolius extract (TGE) in animal model of FLD induced by high-fat diet (HFD). The standardization of TGE based on phenolic compounds was performed using high-performance liquid chromatography (HPLC) analysis. The HFD induced metabolic and hepatic damages. TGE significantly reduced the elevations of serum triglyceride, cholesterol, low-density lipoprotein (LDL), and hepatic enzymes (p =.001 for 25, 50, and 100 mg/kg of TGE). Histopathological studies also confirmed beneficial effects of TGE in FLD. Activity of total antioxidant power, content of total thiol, myeloperoxidase (MPO) enzyme activity, and lipid peroxidation were significantly improved (p <.001). Dietary supplementation with TGE results in improvement of biochemical as well as histopathological parameters. Clinical trials are warranted to prove its efficacy and tolerability in patients with FLD.
Full text links
Related Resources
Trending Papers
Heart failure with preserved ejection fraction: diagnosis, risk assessment, and treatment.Clinical Research in Cardiology : Official Journal of the German Cardiac Society 2024 April 12
Proximal versus distal diuretics in congestive heart failure.Nephrology, Dialysis, Transplantation 2024 Februrary 30
World Health Organization and International Consensus Classification of eosinophilic disorders: 2024 update on diagnosis, risk stratification, and management.American Journal of Hematology 2024 March 30
Efficacy and safety of pharmacotherapy in chronic insomnia: A review of clinical guidelines and case reports.Mental Health Clinician 2023 October
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app