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JOURNAL ARTICLE
Primary Cell Phenotypic Screening Illuminates ADRs and AOPs.
Cell Chemical Biology 2017 July 21
Preclinical, in vitro screening for adverse drug reactions continues to present challenges in the field of drug development. In this issue of Cell Chemical Biology, Shah et al. (2017) employ a phenotypic screening strategy using a panel of human primary cells to define a signature response and an adverse outcome pathway for delayed type IV skin hypersensitivity.
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