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Journal Article
Research Support, Non-U.S. Gov't
An Interdisciplinary Approach for Designing Kinetic Models of the Ras/MAPK Signaling Pathway.
We present in this article a methodology for designing kinetic models of molecular signaling networks, which was exemplarily applied for modeling one of the Ras/MAPK signaling pathways in the mouse Y1 adrenocortical cell line. The methodology is interdisciplinary, that is, it was developed in a way that both dry and wet lab teams worked together along the whole modeling process.
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