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MicroRNA in hormonal mechanisms of regulation of NK cell function.

S V Shirshev, I V Nekrasova, O L Gorbunova, E G Orlova, I L Maslennikova
Doklady. Biochemistry and Biophysics 2017 May
We investigated the effect of human chorionic gonadotropin, estriol, leptin, ghrelin, and kisspeptin on the microRNA expression in separated NK cells. All of these hormones are able to effectively modulate the expression of microRNAs both stimulating and suppressing the cytotoxic potential of NK cells and thereby indirectly regulate the functions of these lymphocytes.

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