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Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
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HDAC Inhibitors Finally Open Up: Chromatin Accessibility Signatures of CTCL.

Christopher J Ott, Catherine J Wu
Cancer Cell 2017 July 11
In this issue of Cancer Cell, Qu et al. describe the chromatin accessibility profiles of cutaneous T cell lymphoma, with dynamic assessments of response and resistance to histone deacetylase inhibitor therapy. Their "personal regulome" analysis framework reveals chromatin features that may be predictive of clinical response to epigenetic therapy.

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