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The role of magnesium sulfate in the intensive care unit.

Yunes Panahi, Mojtaba Mojtahedzadeh, Atabak Najafi, Mohammad Reza Ghaini, Mohammad Abdollahi, Mohammad Sharifzadeh, Arezoo Ahmadi, Seyyed Mahdi Rajaee, Amirhossein Sahebkar
EXCLI Journal 2017
Magnesium (Mg) has been developed as a drug with various clinical uses. Mg is a key cation in physiological processes, and the homeostasis of this cation is crucial for the normal function of body organs. Magnesium sulfate (MgSO4 ) is a mineral pharmaceutical preparation of magnesium that is used as a neuroprotective agent. One rationale for the frequent use of MgSO4 in critical care is the high incidence of hypomagnesaemia in intensive care unit (ICU) patients. Correction of hypomagnesaemia along with the neuroprotective properties of MgSO4 has generated a wide application for MgSO4 in ICU.

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