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JOURNAL ARTICLE
REVIEW
Pharmacoeconomics of Orphan Disease Treatment with a Focus on Hereditary Angioedema.
Immunology and Allergy Clinics of North America 2017 August
This article discusses orphan diseases, their prevalence, legislative incentives to encourage development of therapies, and the impact of treatment on health care payment systems. Specifically, the cost burden of hereditary angioedema on patients, health care systems, and society is reviewed. The impact of availability of and access to novel and specific therapies on morbidity, mortality, and overall burden of disease is explored. Changes in treatment paradigms to improve effect and reduce cost of treatment are presented.
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