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Retinoic Acid Puts Hematopoietic Stem Cells Back To Sleep.

Alexandra Rundberg Nilsson, Cornelis Jan Pronk
Cell Stem Cell 2017 July 7
Dormant hematopoietic stem cells (dHSCs) display superior serial reconstitution capacity compared to active HSCs, although their role in normal hematopoiesis has not been thoroughly investigated. Recently in Cell, Cabezas-Wallscheid et al. (2017) demonstrate involvement of retinoic acid signaling in murine dHSCs for preservation of the HSC pool.

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