Sensitivity and specificity of Matrix-Associated Laser Desorption/Ionization - Time of Flight Mass Spectrometry (MALDI-TOF MS) in discrimination at species level for Acinetobacter bacteremia.

Meng-San Wu, Sophie Collier, Po-Yu Liu, Yi-Tzu Lee, Shu-Chen Kuo, Ya-Sung Yang, Te-Li Chen, Zi-Yuan Shi, Chin-Fu Lin

Journal of Microbiological Methods 2017 September

We aimed to establish the role of MALDI-TOF MS on species discrimination of phenotypically indistinguishable A. baumannii, A. pittii and A. nosocomialis. Compared to multiplex PCR, the gold standard, MALDI-TOF MS yielded a high sensitivity for A. baumannii (97.9%) and specificity for A. pittii (98.9%) and A. nosocomialis (100%).

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