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Double duplex invasion of DNA induced by ultrafast photo-cross-linking using 3-cyanovinylcarbazole for antigene methods.

Shigetaka Nakamura, Hayato Kawabata, Kenzo Fujimoto
Chemical Communications : Chem Comm 2017 July 5
In the creation of double duplex formation with genomic DNA, the probe must be able to invade and hybridize to the duplex DNA. We designed new photoresponsive probes containingCNV K andCN U; these probes have a high double-duplex invasion capability upon photoirradiation.

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