JOURNAL ARTICLE
RESEARCH SUPPORT, NON-U.S. GOV'T
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A stitch in time: Replicate early and escape dosage compensation to express more.

The biological significance of conserved replication timing patterns in eukaryotic genomes remains a mystery. In this issue, Müller and Nieduszynski (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201701061) find that early replication is a requirement for the highest expression levels of certain genes.

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