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Assessment and estimation of 67 Cu production yield via deuteron induced reactions on nat Zn and 70 Zn.

67 Cu radioisotope is a beta particle-emitting nuclide used in radioimmunotherapy (RIT) as well as for imaging, tracer kinetic studies and dosimetry.67 Cu can be produced by bombardingnat Zn with deuterons. In this study, the physical yields of67 Cu vianat Zn(d,x)67 Cu reaction channel as well as via subreactions of68 Zn(d,2pn)67 Cu,67 Zn(d,2p)67 Cu,70 Zn(d,2p3n)67 Cu,68 Zn(d,x)67 Ni(T1/2 =21s)→67 Cu and70 Zn(d,x)67 Ni(T1/2 =21s)→67 Cu in thenat Zn target have been calculated by using the MCNPX-2.6, TALYS-1.8 and SRIM codes. Also, the total cross sections for production of67 Cu fromnat Zn(d,x)67 Cu reaction channel in the energy range of 15-45MeV have been estimated by TALYS code. The best reaction to produce67 Cu radionuclide in a carrier free form was chosen with deuteron energy around 30MeV on70 Zn thick target. Good agreement between the calculated results and the experimental values shows that the employed methods can be used for prediction and production estimation in cyclotron.

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