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JOURNAL ARTICLE
RESEARCH SUPPORT, NON-U.S. GOV'T
Organocatalytic Direct N-Acylation of Amides with Aldehydes under Oxidative Conditions.
Journal of Organic Chemistry 2017 July 8
The direct oxidative N-acylation reaction of primary amides with aryl/α,β-unsaturated aldehydes was achieved in the presence of azolium salt C3 and an inorganic base using 3,3',5,5'-tetra-tert-butyldiphenoquinone as the oxidant, thus providing an efficient approach for the synthesis of three types of imide compounds including N-sulfonylcarboxamides, N-sulfinylcarboxamides, and dicarboxyimides in good yield.
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