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Type I Interferons Interfere with Liver Glucose Metabolism.

Güneş Parlakgul, Gökhan S Hotamisligil
Cell Metabolism 2017 June 7
The specific immunological components linking metabolic stresses to liver inflammation and systemic metabolic pathologies in obesity are not entirely known. A recent study (Ghazarian et al., 2017) reveals that obesity-induced type I interferon signaling drives the accumulation and activation of intrahepatic CD8(+) T cells, leading to systemic metabolic deterioration.

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