We have located links that may give you full text access.
In vitro degradation of polydimethylsiloxanes in breast implant applications.
Journal of Applied Biomaterials & Functional Materials 2017 November 11
BACKGROUND: The durability of breast implant material is associated with failure probability, increasing with time from implantation. The current study avoided the bias introduced by biological factors, to systematically investigate the degradation over time of shell materials. The same fundamental physical and chemical conditions were maintained (temperature and pH) throughout the study, to decouple biological aspects from the degradation process.
METHODS: Six virgin implants of 2 brands were submitted to the in vitro degradation process, mechanical testing of shell materials, surface change analysis (via scanning electron microscopy [SEM]) and chemical composition analysis by Fourier transform infrared (FTIR) spectroscopy.
RESULTS: FTIR results showed that the principal chemical bonds of the material remained intact after 12 weeks of degradation. Apparently the implants' shell structures remained unchanged. Despite this observation, there were statistically significant differences between strain at failure at different time points for the shells of both brands, translated into a stiffening of the material over time.
CONCLUSIONS: Material stiffening is reported as an indicator of material degradation. This altered mechanical behavior, added to the mechanical friction from tissue-tissue and tissue-implant contact and to the external mechanical loading (physical activity), may alter the material performance in women's bodies. Ultimately these changes may affect the implants' durability. Further work is needed to understand the biological aspects of the degradation process and their impact on implant durability.
METHODS: Six virgin implants of 2 brands were submitted to the in vitro degradation process, mechanical testing of shell materials, surface change analysis (via scanning electron microscopy [SEM]) and chemical composition analysis by Fourier transform infrared (FTIR) spectroscopy.
RESULTS: FTIR results showed that the principal chemical bonds of the material remained intact after 12 weeks of degradation. Apparently the implants' shell structures remained unchanged. Despite this observation, there were statistically significant differences between strain at failure at different time points for the shells of both brands, translated into a stiffening of the material over time.
CONCLUSIONS: Material stiffening is reported as an indicator of material degradation. This altered mechanical behavior, added to the mechanical friction from tissue-tissue and tissue-implant contact and to the external mechanical loading (physical activity), may alter the material performance in women's bodies. Ultimately these changes may affect the implants' durability. Further work is needed to understand the biological aspects of the degradation process and their impact on implant durability.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app