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Bright red-emitting pyrene derivatives with a large Stokes shift for nucleus staining.

Chathura S Abeywickrama, Kaveesha J Wijesinghe, Robert V Stahelin, Yi Pang
Chemical Communications : Chem Comm 2017 May 31
A highly fluorescent red-emitting pyrene derivative was synthesized and found to exhibit a large Stokes shift (λem ≈ 610 nm, Δλ ∼ 130 nm, Δν ∼ 4597 cm-1 ). The probe molecule showed remarkable selectivity to stain the nucleus in both live and fixed cells, with higher sensitivity than commercial dye DRAQ5.

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