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Two new compounds from the fruiting bodies of Ganoderma philippii.

Shuang Yang, Qing-Yun Ma, Fan-Dong Kong, Qing-Yi Xie, Sheng-Zhuo Huang, Li-Man Zhou, Hao-Fu Dai, Zhi-Fang Yu, You-Xing Zhao
Journal of Asian Natural Products Research 2018 March
Two new compounds, philippin (1) and 3β,9α,14α-trihydroxy-(22E,24R)-ergost-22-en-7-one (2), were isolated from the fruiting bodies of Ganoderma philippii. Their structures were elucidated on the basis of the spectroscopic technologies, including 1D and 2D NMR as well as MS. The bioassay of inhibitory activity against acetylcholinesterase (AChE) showed compound 1 exhibited weak inhibitory activity against AChE.

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