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Engineering CAR T Cells with Biomaterials.

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Cancer Discovery 2017 July
Incorporating biomaterials into the design of CAR T cells may yield new, improved versions of this immunotherapy. Two preclinical studies indicate the potential of using biodegradable nanoparticles to program circulating T cells into CAR T cells in situ , and delivering these therapeutic cells directly to solid tumors via small dissolvable sponges.

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