Evaluation Studies
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Development of a Chlorantraniliprole Microcapsule Formulation with a High Loading Content and Controlled-Release Property.

Microcapsule formulations have been widely developed and used in agriculture to improve pesticide utilization and reduce environmental pollution. However, commercial formulations of chlorantraniliprole (CAP) are only traditional formulations due to poor solubility of CAP in organic solvents. Here, adopting a solid in oil in water (S/O/W) double-emulsion method combined with premix membrane emulsion, we successfully constructed CAP microcapsule formulations with a high loading content. The microcapsule formulations with good light and thermal stability showed a significantly sustained release for a long period, which could be optimally regulated by tuning the surface porosity and size of the porous microcapsules. Bioassay studies showed that control efficacy of the porous microcapsule formulations against Plutella xylostella was superior to that of the commercial formulation. These results demonstrated that such a porous microcapsule delivery system should have great potential for further exploration as a commercial CAP formulation.

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