We have located links that may give you full text access.
Journal Article
Review
The Influence of Inflammatory Cytokines on the Proliferation and Osteoblastic Differentiation of MSCs.
BACKGROUND: Mesenchymal stem cells (MSCs) have been widely researched for the function of wound repair and bone regeneration. Numerous evidence have proved that MSCs can differentiate towards osteoblasts, and enhance bone formation, and then directly promote the process of bone regeneration.
OBJECTIVE: The researchers' interest in MSCs focuses on the potential of differentiating towards osteoblasts. They suggest that these applications can be significantly influenced by different kinds of inflammatory cytokines. In particular, in the process of bone regeneration, MSCs and inflammatory cytokines interact with each other, and promote the process of bone healing. In this review, we attempt to summarize several inflammatory cytokines that may have influence on the osteogenic differentiation of MSCs, including interleukin 1 (IL-1), IL-6, IL-10, IL-17, tumor necrosis factor-α (TNF-α), and interferon-γ (INF-γ), bone morphogenetic proteins(BMPs). Finally, some perspective of the behavior of MSCs in response to inflammatory cytokines are discussed.
OBJECTIVE: The researchers' interest in MSCs focuses on the potential of differentiating towards osteoblasts. They suggest that these applications can be significantly influenced by different kinds of inflammatory cytokines. In particular, in the process of bone regeneration, MSCs and inflammatory cytokines interact with each other, and promote the process of bone healing. In this review, we attempt to summarize several inflammatory cytokines that may have influence on the osteogenic differentiation of MSCs, including interleukin 1 (IL-1), IL-6, IL-10, IL-17, tumor necrosis factor-α (TNF-α), and interferon-γ (INF-γ), bone morphogenetic proteins(BMPs). Finally, some perspective of the behavior of MSCs in response to inflammatory cytokines are discussed.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app