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Eyeing the Fountain of Youth.

Magali Saint-Geniez, Mariana Aparecida B Rosales
Cell Stem Cell 2017 May 5
Stem cell-based disease modeling is an emerging technology for the mechanistic study and therapeutic screening of complex ocular pathologies. In this issue of Cell Stem Cell, Saini et al. (2017) show that iPSC-derived RPE cells from age-related macular degeneration patients express increased levels of pro-inflammatory factors that can be normalized by the anti-aging drug nicotinamide.

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