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Synthetic Embryos: Windows into Mammalian Development.

Aryeh Warmflash
Cell Stem Cell 2017 May 5
Mammalian embryonic stem cells (ESCs) can self-organize in vitro, but whether they can recreate early embryonic morphogenesis is unclear. Harrison et al. recently demonstrate in Science that 3D co-cultures of mouse ESCs and trophoblast stem cells self-organize into embryo-like structures that recreate many features of early mouse development.

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