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Activity-based assessment of an engineered hyperthermophilic protein as a capture agent in paper-based diagnostic tests.
Molecular Systems Design & Engineering 2016 December 2
Antibodies have traditionally served as the affinity reagents of choice in point-of-care diagnostic biosensors. However, this class of proteins is not ideally suited for this use, being poorly characterized and prone to thermal denaturation. Here, we present an activity-based assessment of an alternative engineered binding protein in a cellulose-based assay.
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