We have located links that may give you full text access.
Glycated albumin is stable in plasma when exposed to common laboratory conditions and comparable when drawn from venous or capillary sites.
Journal of Clinical Laboratory Analysis 2018 Februrary
BACKGROUND: Circulating glycated albumin is a marker of blood glucose reflecting the previous 2 weeks. However, the effects of storage conditions and draw site on glycated albumin values are not fully understood.
METHODS: Fifteen plasma samples from people with type 2 diabetes were assessed during repeated freeze-thaw rounds for 10 cycles. A further 15 samples were stored at 4°C and assessed over 3 days. Another 40 samples drawn concurrently from capillary and venous sites had their glycated albumin content compared.
RESULTS: Glycated albumin concentration did not alter over 10 freeze-thaw cycles (P=.856), or after 72 hours at 4°C (P=.962). Capillary and venous samples did not differ in their percentage of glycated albumin (P=.379), although lower concentrations of albumin and glycated albumin (g/dL) were observed in the capillary sample (P<.001).
CONCLUSION: Glycated albumin in plasma appears relatively stable when exposed to common laboratory conditions, reducing a potential confounder to its use as a marker of blood glucose control. The glycated albumin (%) in samples from capillary and venous sites was comparable, suggesting the potential of rapid or portable assessment devices that require a finger prick.
METHODS: Fifteen plasma samples from people with type 2 diabetes were assessed during repeated freeze-thaw rounds for 10 cycles. A further 15 samples were stored at 4°C and assessed over 3 days. Another 40 samples drawn concurrently from capillary and venous sites had their glycated albumin content compared.
RESULTS: Glycated albumin concentration did not alter over 10 freeze-thaw cycles (P=.856), or after 72 hours at 4°C (P=.962). Capillary and venous samples did not differ in their percentage of glycated albumin (P=.379), although lower concentrations of albumin and glycated albumin (g/dL) were observed in the capillary sample (P<.001).
CONCLUSION: Glycated albumin in plasma appears relatively stable when exposed to common laboratory conditions, reducing a potential confounder to its use as a marker of blood glucose control. The glycated albumin (%) in samples from capillary and venous sites was comparable, suggesting the potential of rapid or portable assessment devices that require a finger prick.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app