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Inducible epitope imprinting: 'generating' the required binding site in membrane receptors for targeted drug delivery.
Nanoscale 2017 May 5
We report an inducible epitope imprinting strategy that as a template, a flexible peptide chain can have a disordered-to-ordered conformational change by suitable inducement through a molecular imprinting procedure, and the formed nanoparticles can, in turn, remold the original peptide into the expected conformation and specifically bind to the corresponding protein.
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