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Azithromycin Resistance and Decreased Ceftriaxone Susceptibility in Neisseria gonorrhoeae, Hawaii, USA.

John R Papp, A Jeanine Abrams, Evelyn Nash, Alan R Katz, Robert D Kirkcaldy, Norman P O'Connor, Pamela S O'Brien, Derek H Harauchi, Eloisa V Maningas, Olusegun O Soge, Ellen N Kersh, Alan Komeya, Juval E Tomas, Glenn M Wasserman, Gail Y Kunimoto, David L Trees, A Christian Whelen
Emerging Infectious Diseases 2017 May
During 2016, eight Neisseria gonorrhoeae isolates from 7 patients in Hawaii were resistant to azithromycin; 5 had decreased in vitro susceptibility to ceftriaxone. Genomic analysis demonstrated a distinct phylogenetic clade when compared with local contemporary strains. Continued evolution and widespread transmission of these strains might challenge the effectiveness of current therapeutic options.

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