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Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review
Influenza-induced lung T rm : not all memories last forever.
Immunology and Cell Biology 2017 September
In the light of new findings that lung tissue resident memory CD8+ T cells (Trm ) represent major mediators of heterosubtypic immunity against influenza virus, it is of utmost importance to understand the basic biological mechanisms behind induction, formation and maintenance of this cell population. Addressing these important knowledge gaps will potentially inform development of superior, broadly protective influenza vaccines and new immunization strategies.
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