A new polyketide glycoside from the rhizospheric Clonostachys rogersoniana associated with Panax notoginseng.

A new polyketide glycoside rogerson A (1), along with two known compounds, rogerson B (2) and (22E)-5α,8α-epidioxyergosta-6,22-dien-3β-ol (3), was obtained from the solid fermentation of Clonostachys rogersoniana, which was isolated from the rhizosphere soil of Panax notoginseng. Rogerson B (2) was isolated for the first time from a natural source. Their structure was determined by extensive analyses of NMR and MS studies. Compounds 1 and 2 were tested for its cytotoxicity against five human cancer cell lines.