Photoredox-catalyzed oxytrifluoromethylation of allenes: stereoselective synthesis of 2-trifluoromethylated allyl acetates.

We have developed novel oxytrifluoromethylation of aryl-substituted allenes by photoredox catalysis. The present photocatalytic system allows direct and stereoselective synthesis of 2-CF3 -allyl acetates bearing tetrasubstituted CF3 -alkene scaffolds in a single operation. The obtained CF3 -allyl acetates can be applied to further functionalization as CF3 -containing building blocks.