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Journal Article
Research Support, Non-U.S. Gov't
Salivary Prostaglandin E2: Role in Tick-Induced Allergy to Red Meat.
Trends in Parasitology 2017 July
Tick-induced allergy to red meat is associated with anti-α-Gal IgE antibody levels. We propose that tick salivary prostaglandin E2 triggers antibody class switching in mature B cells, increasing the levels of anti-α-Gal IgE antibodies. Immune tolerance to α-Gal in blood type B individuals might reduce the risk to this allergy.
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