A New Reactive 1,8-Naphthalimide Derivative for Highly Selective and Sensitive Detection of Hg 2 .

A 1,8-naphthalimide derivative with a reactive aliphatic hydroxyl was designed and synthesized as a fluorescent probe. Its structure was characterized by IR,1 H NMR,13 C NMR, LC-MS and HPLC. The probe showed high selectivity and sensitivity to Hg2+ over other metal ions such as Pb2+ , Na+ , K+ , Cd2+ , Cr3+ , Zn2+ , Cu2+ , Ni2+ , Ca2+ , Fe3+ , Fe2+ , Co2+ , Mn2+ and Mg2+ in MeCN/H2 O (15/85, v/v). The increase in fluorescence intensity was linearly proportional to the concentration of Hg2+ in the range of 18-40 μM with a detection limit of 1.38 × 10-7  mol/L. The probe could work in a pH span of 4.3-9.0 and respond to Hg2+ quickly with strong anti-interference ability. Job's plot suggested a 1:2 complex of the probe and Hg2+ .