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JOURNAL ARTICLE
META-ANALYSIS
REVIEW
Meta-analysis of Transhiatal Esophagectomy in carcinoma of esophagogastric junction, does it have an advantage?
International Journal of Surgery 2017 June
PURPOSE: Compare the clinical outcome of Transhiatal Esophagectomy (THE) approach and open Thoracic Esophagectomy (TTE) approach in the carcinoma of esophagogastric junction (CEGJ).
METHODS: Relevant literature published until 2016 from PubMed, Cochrane Library, Ovid (Medline) and EMBASE were retrieved. Meta-analysis was achieved by using the Stata12 software.
RESULTS: A total of 18 studies and 2202 cases of patients were involved in this meta-analysis. THE showed to decrease the hospital stay, hospital mortality, surgical time, and blood loss in the operation. However, fewer lymph nodes would be yielded by this surgical option. A 5-year survival advantage of THE was only observed in North America subgroup.
CONCLUSIONS: Except the above operative related advantages, there was no clear evidence that THE has a further advantage in CEGJ.
METHODS: Relevant literature published until 2016 from PubMed, Cochrane Library, Ovid (Medline) and EMBASE were retrieved. Meta-analysis was achieved by using the Stata12 software.
RESULTS: A total of 18 studies and 2202 cases of patients were involved in this meta-analysis. THE showed to decrease the hospital stay, hospital mortality, surgical time, and blood loss in the operation. However, fewer lymph nodes would be yielded by this surgical option. A 5-year survival advantage of THE was only observed in North America subgroup.
CONCLUSIONS: Except the above operative related advantages, there was no clear evidence that THE has a further advantage in CEGJ.
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