Highly sensitive electrochemical sensor for chloramphenicol based on MOF derived exfoliated porous carbon.

Benefit from the advantages in costless, simplicity and efficiency, solvent exfoliation has been widely used in preparation of two-dimensional nanosheets with enhanced performances in electronics, photonics, and catalysis. In this work, solvent exfoliation was first applied to prepare exfoliated porous carbon (EPC) from an isoreticular metal-organic framework-8 (IRMOF-8) derived porous carbon (DPC). The obtained EPC with high surface area (1854m2 g-1 ) and improved dispersibility was used as electrode modifier for glassy carbon electrode (GCE) in square wave voltammetry (SWV) detection of chloramphenicol (CAP). The sensitivity of EPC modified GCE (EPC/GCE) was greatly improved in compare with that of the DPC modification. The corresponding linear ranges are 1×10-8 -1×10-6 molL-1 and 1×10-6 -4×10-6 molL-1 . The detection limit was calculated to be 2.9×10-9 molL-1 (at a signal-to-noise ratio of 3, S/N=3). In addition, the proposed sensor was successfully applied in the analysis of CAP in honey and achieved satisfying recovery.