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Comparative Study
Journal Article
[Comparative Prospective Clinical Economic Study of Original and Generic Bisoprolol in Patients With Coronary Heart Disease].
Kardiologiia 2016 May
PURPOSE: to conduct comparative clinical and economical analysis of original and generic preparations of bisoprolol.
MATERIALS AND METHODS: The study included 61 patients after acute coronary syndrome (ACS) (34 men, 27 women, age 46-78 years). Patients were distributed (envelope method) to 2 groups. Patients of group A received original bisoprolol, of group C - generic drug. Duration of observation was 6 weeks. Parameters analyzed were dynamics of heart rate (HR), data of treadmill exercise test, and values of calculated cost/effectiveness ratio.
RESULTS: In both groups we observed significant slowing of HR. Data of treadmill test showed similar increases of volume of work.
MATERIALS AND METHODS: The study included 61 patients after acute coronary syndrome (ACS) (34 men, 27 women, age 46-78 years). Patients were distributed (envelope method) to 2 groups. Patients of group A received original bisoprolol, of group C - generic drug. Duration of observation was 6 weeks. Parameters analyzed were dynamics of heart rate (HR), data of treadmill exercise test, and values of calculated cost/effectiveness ratio.
RESULTS: In both groups we observed significant slowing of HR. Data of treadmill test showed similar increases of volume of work.
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