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Observational Study
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
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Sex differences in gout characteristics: tailoring care for women and men.

Leslie R Harrold, Carol J Etzel, Allan Gibofsky, Joel M Kremer, Michael H Pillinger, Kenneth G Saag, Naomi Schlesinger, Robert Terkeltaub, Vanessa Cox, Jeffrey D Greenberg
BMC Musculoskeletal Disorders 2017 March 15
BACKGROUND: To characterize the differences between women and men with gout.

METHODS: We analyzed a US national cohort of gout patients cared for by rheumatologists.

RESULTS: Compared with the 1012 men with gout, women with gout (n = 262) were older (71 vs. 61 years, p < 0.001) and had a greater burden of comorbid conditions (p < 0.001 for hypertension, diabetes, renal disease and obesity). Risk factors for gout differed with women more often taking diuretics (p < 0.001), while men more frequently had dietary triggers (p < 0.05).

CONCLUSIONS: The profiles of women and men with gout are markedly different, suggesting a need to tailor treatment recommendations.

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