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JOURNAL ARTICLE
Bioengineered 3D Models for Studying Human Cell-Tuberculosis Interactions.
Trends in Microbiology 2017 April
In vivo animal models have intrinsic limitations for studying relationships between tuberculosis and its host and there is a need for alternative, in vitro cellular models. A microsphere-based 3D in vitro culture system of Mycobacterium tuberculosis-infected human blood mononuclear cells was reported to address specific aspects of host-pathogen interactions.
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