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Case Reports
Journal Article
BCG and Kawasaki disease in Mexico and Japan.
Human Vaccines & Immunotherapeutics 2017 May 5
Dr. Tomisaku Kawasaki was the first to describe BCG reactivation in Kawasaki Disease (KD ), and this sign is present in about 30-50% of KD patients. It is a very specific early sign of the disease and although it has been recognized for decades, its pathophysiology continues to be an enigma. Recently, Yamada et al. reported a severe BCG reaction with tuberculid in 2 Japanese KD patients. We present 2 cases with KD and severe BCG reaction, one from Japan and the other from Mexico and review the policies of administration of BCG in both countries. The BCG vaccine has a worldwide coverage of 88%. Differences in BCG strains and methods of administration may influence BCG reactions in KD . The BCG reaction in the inoculation site may represent the most useful sign in KD .
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