Translation and validation of the 15-item Myasthenia Gravis Quality of life scale in Dutch.

INTRODUCTION: The 15-item Myasthenia Gravis Quality of Life (MG-QOL15) scale has been developed to assess the health-related quality of life of patients with myasthenia gravis (MG). The aim of this study was to translate the original English version into Dutch and to test the test-retest reliability and construct validity.

METHODS: Fifty patients with MG were included. Test-retest reliability and internal consistency were assessed using the intraclass correlation coefficient (ICC) and the Cronbach α. Construct validity was assessed by testing 5 predefined hypotheses.

RESULTS: A good test-retest reliability was confirmed with an ICC of 0.866. The Cronbach α was 0.93. The predefined hypotheses were confirmed in 80% of cases, which points to good construct validity.

DISCUSSION: The Dutch MG-QOL15 has good test-retest reliability and good construct validity. It can be used for research in a Dutch-speaking population. It is also suitable for monitoring individual patients in clinical practice. Muscle Nerve 57: 206-211, 2018.