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JOURNAL ARTICLE
REVIEW
The how, why and clinical importance of stratum corneum acidification.
Experimental Dermatology 2017 November
In this article, I review the multiple endogenous mechanisms that contribute to the highly acidic pH of normal stratum corneum (SC). Then, I describe how each mechanism potentially impacts specific defensive functions of the SC. Finally, I review the rapidly expanding, clinical implications and potential therapeutic applications of SC acidification.
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