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Choosing the right heart: proper donor selection in cardiac transplantation.
Current Opinion in Cardiology 2017 Februrary 25
PURPOSE OF REVIEW: Orthotopic heart transplantation remains a definitive treatment for advanced heart failure. This review describes, on an individual patient level, how best to select donor hearts.
RECENT FINDINGS: In selecting hearts, recipient health factors and comorbidities tend to outweigh most donor factors. Expanded donor criteria will allow for transplanting a larger group of patients. More work remains on developing scoring systems, ex-vivo perfusion of the donor heart, and use of donor biomarkers.
SUMMARY: Considering the power of the donor heart allows for optimization of donor-recipient matching.
RECENT FINDINGS: In selecting hearts, recipient health factors and comorbidities tend to outweigh most donor factors. Expanded donor criteria will allow for transplanting a larger group of patients. More work remains on developing scoring systems, ex-vivo perfusion of the donor heart, and use of donor biomarkers.
SUMMARY: Considering the power of the donor heart allows for optimization of donor-recipient matching.
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