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CASE REPORTS
JOURNAL ARTICLE
Histologic transformation of EGFR mutant lung adenocarcinoma without exposure to EGFR inhibition.
Resistance to EGFR kinase inhibitors appears to be invariable in the treatment of non-small cell lung cancer. Several mechanisms have been described. Here, we report the first case of histologic transformation of EGFR mutant lung adenocarcinoma without prior exposure to EGFR inhibition.
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