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Journal Article
Research Support, Non-U.S. Gov't
Assembly of Diversely Substituted Quinolines via Aerobic Oxidative Aromatization from Simple Alcohols and Anilines.
Journal of Organic Chemistry 2017 March 18
An aerobic oxidative aromatization of simple aliphatic alcohols and anilines under the Pd(OAc)2 /2,4,6-Collidine/Brønsted acid catalytic system has been established, providing a direct approach for the preparation of diverse substituted quinoline derivatives in high yields with wide functional group tolerance. Practically, the protocol can be easily scaled up to gram-scale and was utilized in the concise formal synthesis of a promising herbicide candidate.
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